Announcements and Notices - [Notice of AGM / Re-election or Appointment of Director subject to Shareholders' Approval / Closure of Books or Change of Book Closure Period] SUPPLEMENTAL NOTICE OF ANNUAL GENERAL MEETING

Proxy Forms REVISED FORM OF PROXY FOR THE ANNUAL GENERAL MEETING TO BE HELD AT THEATER R1, 10/F, UNITED CENTRE, 95 QUEENSWAY, ADMIRALTY, HONG KONG ON TUESDAY, 15 JUNE 2021 AT 10:00 A.M.

Circulars - [Re-election or Appointment of Director subject to Shareholders' Approval / Explanatory Statement for Repurchase of Shares / General Mandate] PROPOSED ELECTION OF INDEPENDENT NON-EXECUTIVE DIRECTOR AND SUPPLEMENTAL NOTICE OF ANNUAL GENERAL MEETING

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 April 2021

Announcements and Notices - [Notice of AGM / Re-election or Appointment of Director subject to Shareholders' Approval / Closure of Books or Change of Book Closure Period] NOTICE OF ANNUAL GENERAL MEETING

Proxy Forms FORM OF PROXY FOR THE ANNUAL GENERAL MEETING TO BE HELD AT THEATER R1, 10/F, UNITED CENTRE, 95 QUEENSWAY, ADMIRALTY, HONG KONG ON TUESDAY, 15 JUNE 2021 AT 10:00 A.M.

Circulars - [Re-election or Appointment of Director subject to Shareholders' Approval / Explanatory Statement for Repurchase of Shares / General Mandate] PROPOSED RE-ELECTION OF RETIRING DIRECTORS AND PROPOSED GRANTING OF GENERAL MANDATES TO BUY BACK SHARES AND TO ISSUE SHARES AND NOTICE OF ANNUAL GENERAL MEETING

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 March 2021

Announcements and Notices - [Final Results / Dividend or Distribution / Closure of Books or Change of Book Closure Period] ANNUAL RESULTS ANNOUNCEMENT FOR THE YEAR ENDED 31 DECEMBER 2020

Announcements and Notices - [Connected Transaction] ANNOUNCEMENT - CONNECTED TRANSACTION UNDER LEASE AGREEMENT

Announcements and Notices - [Date of Board Meeting] DATE OF BOARD MEETING

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 28 February 2021

Announcements and Notices - [Results of EGM/SGM] POLL RESULTS OF THE EXTRAORDINARY GENERAL MEETING HELD ON 19 FEBRUARY 2021

Announcements and Notices - [Discloseable Transaction] SUPPLEMENTAL ANNOUNCEMENT

Announcements and Notices - [Other - Miscellaneous] ADOPTION OF SHARE AWARD SCHEME

Announcements and Notices - [Discloseable Transaction] DISCLOSEABLE TRANSACTION - DISPOSAL OF CHINA HEALTHCARE FUND

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 January 2021

Proxy Forms FORM OF PROXY FOR THE EXTRAORDINARY GENERAL MEETING TO BE HELD AT THEATER R1, 10/F, UNITED CENTRE, 95 QUEENSWAY, ADMIRALTY, HONG KONG ON FRIDAY, 19 FEBRUARY 2021 AT 10:00 A.M.

Announcements and Notices - [Notice of EGM/SGM / Closure of Books or Change of Book Closure Period] NOTICE OF EXTRAORDINARY GENERAL MEETING

Circulars - [Connected Transaction / Issue of Convertible Securities / Issue of Shares] (1) CONNECTED TRANSACTION - PROPOSED ISSUE OF HK$100,000,000 CONVERTIBLE BONDS DUE 2022 POSSIBLE ISSUE OF SHARES UNDER SPECIFIC MANDATE AND (2) NOTICE OF EGM

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT - FIRST HEALTHY SUBJECT DOSED IN A PHASE I CLINICAL TRIAL OF SN1011 IN CHINA

Announcements and Notices - [Delay in Dispatch of Circular or other Document / Issue of Shares under a Specific Mandate / Issue of Convertible Securities / Connected Transaction] DELAY IN DESPATCH OF CIRCULAR

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 December 2020