Announcements and Notices - [Connected Transaction] CONNECTED TRANSACTION SUPPLEMENTAL LEASE AGREEMENT

Announcements and Notices - [Change in Company Secretary] CHANGE OF COMPANY SECRETARY

Next Day Disclosure Returns - [Others] Next Day Disclosure Return

Announcements and Notices - [Issue of Shares under a General Mandate] COMPLETION OF SUBSCRIPTIONS OF NEW SHARES UNDER GENERAL MANDATE

Announcements and Notices - [Issue of Shares under a General Mandate] SUPPLEMENTAL ANNOUNCEMENT IN RELATION TO SUBSCRIPTIONS OF NEW SHARES UNDER GENERAL MANDATE

Announcements and Notices - [Share Option Scheme] GRANT OF SHARE OPTIONS

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 October 2022

Announcements and Notices - [Issue of Shares under a General Mandate] SUBSCRIPTIONS OF NEW SHARES UNDER GENERAL MANDATE

Announcements and Notices - [Results of EGM/SGM] POLL RESULTS OF THE EXTRAORDINARY GENERAL MEETING HELD ON 26 OCTOBER 2022

Documents on Display 2022 SHARE OPTION SCHEME

Proxy Forms FORM OF PROXY FOR THE EXTRAORDINARY GENERAL MEETING TO BE HELD AT THEATER R2, 10/F, UNITED CENTRE, 95 QUEENSWAY, ADMIRALTY, HONG KONG ON WEDNESDAY, 26 OCTOBER 2022 AT 10:00 A.M.

Announcements and Notices - [Notice of EGM/SGM / Closure of Books or Change of Book Closure Period] NOTICE OF EXTRAORDINARY GENERAL MEETING

Circulars - [Share Option Scheme] PROPOSAL FOR ADOPTION OF THE 2022 SHARE OPTION SCHEME AND NOTICE OF EXTRAORDINARY GENERAL MEETING

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 September 2022

Announcements and Notices - [Share Option Scheme] PROPOSED ADOPTION OF SHARE OPTION SCHEME

Announcements and Notices - [Notice of EGM/SGM / Closure of Books or Change of Book Closure Period] POSTPONEMENT OF EXTRAORDINARY GENERAL MEETING AND WITHDRAWAL OF THE ORDINARY RESOLUTION

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT UPDATE IN CLINICAL PROGRESS

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 August 2022

Documents on Display 2022 SHARE OPTION SCHEME

Proxy Forms FORM OF PROXY FOR THE EXTRAORDINARY GENERAL MEETING TO BE HELD AT THEATER R2, 10/F, UNITED CENTRE, 95 QUEENSWAY, ADMIRALTY, HONG KONG ON WEDNESDAY, 21 SEPTEMBER 2022 AT 10:00 A.M.

Announcements and Notices - [Notice of EGM/SGM / Closure of Books or Change of Book Closure Period] NOTICE OF EXTRAORDINARY GENERAL MEETING

Circulars - [Share Option Scheme] PROPOSAL FOR ADOPTION OF THE 2022 SHARE OPTION SCHEME AND NOTICE OF EXTRAORDINARY GENERAL MEETING

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT IND APPROVAL FOR SN1011 BY NMPA

Announcements and Notices - [Interim Results] INTERIM RESULTS ANNOUNCEMENT FOR THE SIX MONTHS ENDED 30 JUNE 2022

Announcements and Notices - [Change in Registered Address or Office, Registered Place of Business in HK or Agent for Service of Process in HK] CHANGE OF ADDRESS OF REGISTERED OFFICE

Announcements and Notices - [Date of Board Meeting] DATE OF BOARD MEETING

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 July 2022

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 June 2022

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT FIRST HEALTHY SUBJECT DOSED IN A PHASE I CLINICAL TRIAL OF SM17 IN THE U.S.

Announcements and Notices - [List of Directors and their Role and Function] LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS

Announcements and Notices - [Results of AGM / Change in Directors or of Important Executive Functions or Responsibilities] POLL RESULTS OF THE ANNUAL GENERAL MEETING HELD ON 13 JUNE 2022 AND RETIREMENT OF NON-EXECUTIVE DIRECTOR

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT IND APPLICATION FOR SN1011 ACCEPTED BY NMPA CDE

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 May 2022

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 April 2022

Announcements and Notices - [Notice of AGM / Re-election or Appointment of Director subject to Shareholders' Approval / Closure of Books or Change of Book Closure Period] NOTICE OF ANNUAL GENERAL MEETING

Proxy Forms FORM OF PROXY FOR THE ANNUAL GENERAL MEETING TO BE HELD AT THEATER R1, 10/F, UNITED CENTRE, 95 QUEENSWAY, ADMIRALTY, HONG KONG ON MONDAY, 13 JUNE 2022 AT 10:00 A.M.

Circulars - [Re-election or Appointment of Director subject to Shareholders' Approval / Explanatory Statement for Repurchase of Shares / General Mandate] PROPOSED RE-ELECTION OF RETIRING DIRECTORS AND PROPOSED GRANTING OF GENERAL MANDATES TO BUY BACK SHARES AND TO ISSUE SHARES AND NOTICE OF ANNUAL GENERAL MEETING

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT IND APPROVAL FOR SN1011 BY NMPA

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 March 2022

Announcements and Notices - [Final Results / Dividend or Distribution / Closure of Books or Change of Book Closure Period] ANNUAL RESULTS ANNOUNCEMENT FOR THE YEAR ENDED 31 DECEMBER 2021 AND CHANGE IN USE OF PROCEEDS

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT IND APPROVAL FOR SM17 BY FDA

Announcements and Notices - [Date of Board Meeting] DATE OF BOARD MEETING

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 28 February 2022

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT IND APPLICATION FOR SM17 ACCEPTED BY FDA

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 January 2022

Announcements and Notices - [Other - Business Update] VOLUNTARY ANNOUNCEMENT IND APPLICATION FOR SN1011 ACCEPTED BY NMPA CDE

Monthly Returns Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 December 2021